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Table 1 The results of epigenome-wide association study on systolic blood pressure (p < 1 × 10–4)

From: Epigenome-wide association study in Chinese monozygotic twins identifies DNA methylation loci associated with blood pressure

Chromosome

Position (bp)

Coefficient

p-value

FDR

Ensembl gene ID

HGNC symbol

chr3

84,330,432

 − 0.009

5.756E-06

0.161

ENSG00000242195

SRRM1P2

chr3

84,330,437

 − 0.009

7.677E-06

0.161

ENSG00000242195

SRRM1P2

chr3

84,330,415

 − 0.009

8.172E-06

0.161

ENSG00000242195

SRRM1P2

chr3

84,330,441

 − 0.009

9.579E-06

0.161

ENSG00000242195

SRRM1P2

chr3

84,330,448

 − 0.009

1.248E-05

0.161

ENSG00000242195

SRRM1P2

chr17

58,216,280

 − 0.008

1.285E-05

0.161

ENSG00000267095

NA

chr7

57,472,878

0.013

1.662E-05

0.196

ENSG00000266168

MIR3147

chr8*

9,260,932

 − 0.076

2.635E-05

0.267

ENSG00000254235

NA

     

ENSG00000254237

NA

chr17

58,216,262

 − 0.008

2.687E-05

0.267

ENSG00000267095

NA

chr3

84,330,462

 − 0.008

2.873E-05

0.272

ENSG00000242195

SRRM1P2

chr9

137,673,895

 − 0.009

2.971E-05

0.272

ENSG00000130635

COL5A1

chr9

137,673,907

 − 0.009

3.066E-05

0.272

ENSG00000130635

COL5A1

chr16*

15,814,807

 − 0.048

3.425E-05

0.286

ENSG00000072864

NDE1

     

ENSG00000133392

MYH11

chr13

87,444,790

 − 0.011

3.545E-05

0.286

ENSG00000231879

TXNL1P1

chr18

77,269,485

0.011

4.124E-05

0.320

ENSG00000131196

NFATC1

chr9

137,673,888

 − 0.009

4.699E-05

0.341

ENSG00000130635

COL5A1

chr13

87,444,783

 − 0.011

5.913E-05

0.366

ENSG00000231879

TXNL1P1

chr15

22,545,461

0.007

5.953E-05

0.366

ENSG00000221641

MIR1268A

chr2

130,937,909

0.059

6.043E-05

0.366

ENSG00000136699

SMPD4

chr15

22,545,464

0.007

6.663E-05

0.384

ENSG00000221641

MIR1268A

chr8*

9,260,942

 − 0.071

6.811E-05

0.384

ENSG00000254235

NA

     

ENSG00000254237

NA

chr19

3,670,396

0.010

7.317E-05

0.399

ENSG00000186111

PIP5K1C

chr3

195,609,985

0.050

7.510E-05

0.399

ENSG00000061938

TNK2

chr2

130,937,907

0.055

7.555E-05

0.399

ENSG00000136699

SMPD4

chr1

64,880,619

 − 0.108

7.798E-05

0.403

ENSG00000158966

CACHD1

chr17

19,436,923

 − 0.028

8.193E-05

0.415

ENSG00000142494

SLC47A1

chr18

77,269,508

0.012

8.697E-05

0.428

ENSG00000131196

NFATC1

chr16*

15,814,759

 − 0.056

8.814E-05

0.428

ENSG00000072864

NDE1

     

ENSG00000133392

MYH11

chr18

77,269,476

0.011

8.970E-05

0.428

ENSG00000131196

NFATC1

chr15

22,545,472

0.008

9.480E-05

0.444

ENSG00000221641

MIR1268A

chr17

62,775,172

0.012

9.845E-05

0.450

ENSG00000215769

ARHGAP27P1-BPTFP1-KPNA2P3

  1. NA, not available; FDR, false discovery rate
  2. *The CpG sites annotated to two genes
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Clinical Epigenetics

ISSN: 1868-7083

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