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Table 1 Histopathological diagnoses and methylation-based classifications of the 13 tumour samples with a calibrated score < 0.9

From: Supratentorial CNS-PNETs in children; a Swedish population-based study with molecular re-evaluation and long-term follow-up

Cases

Histopathological re-evaluation

Prediction: family

CS: family

1

HGG NOS

Glioblastoma, IDH-wildtype

0.83808

2

HGG NOS

Pilocytic astrocytoma

0.55519

3

HGG NOS

Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

0.82513

4

HGG NOS

Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

0.65948

5

HGG NOS

Glioblastoma, IDH-wildtype

0.28580

6

Diffuse midline glioma, H3-K27M altered

Diffuse midline glioma, H3K27-altered

0.53717

7

Diffuse hemispheric glioma, H3 G34-mutant

Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

0.50395

8

IHG

Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

0.77386

9

Highly malignant tumor NOS

Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

0.50582

10

CPC

Choroid plexus tumours

0.81520

11

AT/RT

Atypical teratoid rhabdoid tumour

0.70174

12

Ewing tumor with CIC::DUX fusion

NA

NA

13

Unclassifiable

Diffuse pediatric-type high-grade glioma, H3-wildtype and IDH-wildtype

0.71402

  1. HGG NOS, High-grade glioma not otherwise specified; IHG, Infant-type hemispheric glioma; AT/RT, atypical teratoid rhabdoid tumour