Locus | CpG ID | Coefficient | t-value | p-value | Chr | Position | FDR | Gene | BMD association* |
---|---|---|---|---|---|---|---|---|---|
1 | cg03009196 | 9.97E−06 | 6.35 | 1.20E−06 | 1 | 60,392,511 | 0.022 | CYP2J2 | Yes |
2 | cg22010000 | − 1.01E−05 | − 8.55 | 6.89E−09 | 1 | 151,738,555 | 0.002 | OAZ3 | Yes |
3 | cg08901901 | 8.25E−06 | 8.04 | 2.14E−08 | 1 | 160,951,907 | 0.002 |  | No |
4 | cg25619551 | − 9.25E−06 | − 6.59 | 6.62E−07 | 1 | 193,710,042 | 0.015 |  | No |
5 | cg15073625 | − 5.60E−06 | − 5.88 | 3.90E−06 | 2 | 23,862,014 | 0.047 | KLHL29 | Yes |
6 | cg10565322 | − 8.49E−06 | − 6.46 | 9.15E−07 | 2 | 43,136,493 | 0.017 |  | Yes |
7 | cg17641218 | − 9.64E−06 | − 7.78 | 3.87E−08 | 2 | 85,804,603 | 0.002 | VAMP8 | Yes |
8 | cg02494004 | − 8.62E−06 | − 6.35 | 1.21E−06 | 2 | 147,162,808 | 0.022 |  | Yes |
9 | cg06342954 | − 8.24E−06 | − 6.34 | 1.24E−06 | 2 | 236,757,889 | 0.022 | AGAP1 | Yes |
10 | cg14485214 | − 7.96E−06 | − 7.23 | 1.42E−07 | 2 | 241,957,552 | 0.005 | SNED1 | Yes |
11 | cg00227784 | − 7.62E−06 | − 8.76 | 4.33E−09 | 3 | 126,391,755 | 0.002 |  | Yes |
12 | cg14379327 | − 6.77E−06 | − 7.54 | 6.87E−08 | 4 | 146,404,134 | 0.003 | SMAD1 | Yes |
13 | cg20093868 | − 8.86E−06 | − 5.85 | 4.27E−06 | 4 | 152,646,689 | 0.049 | GATB | No |
14 | cg09865379 | − 7.61E−06 | − 5.94 | 3.35E−06 | 4 | 165,708,173 | 0.042 | LINC01207 | No |
15 | cg06753918 | − 5.91E−06 | − 6 | 2.89E−06 | 5 | 6,182,215 | 0.038 |  | No |
16 | cg16653901 | − 9.45E−06 | − 6.27 | 1.48E−06 | 5 | 133,513,511 | 0.025 | SKP1 | No |
17 | cg01247535 | 1.03E−05 | 6.72 | 4.89E−07 | 6 | 15,418,354 | 0.012 | JARID2 | No |
18 | cg17866778 | − 1.58E−05 | − 6.51 | 8.05E−07 | 6 | 26,233,442 | 0.017 |  | Yes |
19 | cg06501109 | − 1.23E−05 | − 6.08 | 2.37E−06 | 6 | 30,850,309 | 0.033 | DDR1 | Yes |
20 | cg17774634 | − 9.25E−06 | − 7.83 | 3.45E−08 | 6 | 97,730,494 | 0.002 | C6orf167;MIR548H3 | No |
21 | cg05923369 | − 1.04E−05 | − 6.47 | 8.93E−07 | 7 | 2,251,548 | 0.017 | MAD1L1 | No |
22 | cg24648241 | − 9.54E−06 | − 5.98 | 3.01E−06 | 7 | 38,347,775 | 0.039 |  | No |
23 | cg14355428 | − 9.62E−06 | − 8.56 | 6.76E−09 | 7 | 91,762,876 | 0.002 | CYP51A1 | Yes |
24 | cg02396891 | − 6.61E−06 | − 6.3 | 1.36E−06 | 7 | 93,222,734 | 0.023 |  | No |
25 | cg10333170 | − 9.21E−06 | − 5.91 | 3.66E−06 | 7 | 134,521,311 | 0.046 | CALD1 | No |
26 | cg22859658 | − 2.03E−05 | − 7.77 | 4.00E−08 | 7 | 144,422,735 | 0.002 | TPK1 | No |
27 | cg10993470 | − 1.05E−05 | − 6.03 | 2.66E−06 | 8 | 55,533,939 | 0.036 | RP1 | No |
28 | cg23855920 | − 9.03E−06 | − 6.24 | 1.58E−06 | 8 | 103,764,916 | 0.026 |  | No |
29 | cg24529650 | − 1.02E−05 | − 7.24 | 1.38E−07 | 9 | 14,031,418 | 0.005 |  | No |
30 | cg13396858 | − 1.05E−05 | − 5.89 | 3.85E−06 | 9 | 134,249,466 | 0.047 |  | Yes |
31 | cg00013660 | − 8.96E−06 | − 7.6 | 5.95E−08 | 9 | 140,068,770 | 0.003 |  | Yes |
32 | cg12368066 | − 1.37E−05 | − 6.93 | 2.88E−07 | 10 | 9,449,275 | 0.008 |  | No |
33 | cg00762372 | − 6.16E−06 | − 6.19 | 1.79E−06 | 10 | 25,618,736 | 0.027 | GPR158 | No |
34 | cg13820475 | − 9.93E−06 | − 6.46 | 9.19E−07 | 10 | 44,461,659 | 0.017 | LINC00841 | No |
35 | ch.10.107354959F | − 9.33E−06 | − 6.53 | 7.69E−07 | 10 | 107,364,969 | 0.017 |  | No |
36 | cg02701677 | − 8.07E−06 | − 7.46 | 8.30E−08 | 11 | 23,970,707 | 0.003 |  | No |
37 | cg08086799 | − 1.20E−05 | − 6.9 | 3.12E−07 | 11 | 62,495,467 | 0.009 | TTC9C;HNRNPUL2 | Yes |
38 | cg22968863 | − 1.03E−05 | − 7.51 | 7.23E−08 | 11 | 72,441,739 | 0.003 | ARAP1 | No |
39 | cg20199739 | 1.88E−05 | 7.03 | 2.30E−07 | 11 | 107,730,522 | 0.007 | SLC35F2 | No |
40 | cg04932413 | − 1.54E−05 | − 6.76 | 4.33E−07 | 14 | 103,002,828 | 0.011 | KLC1 | Yes |
41 | cg01279902 | − 1.01E−05 | − 8.12 | 1.79E−08 | 14 | 104,171,040 | 0.002 | XRCC3 | Yes |
42 | cg04662961 | − 6.63E−06 | − 6.11 | 2.21E−06 | 15 | 44,486,562 | 0.031 | FRMD5 | Yes |
43 | cg27111704 | − 7.75E−06 | − 6.52 | 7.95E−07 | 15 | 83,847,628 | 0.017 | HDGFRP3 | No |
44 | cg16362027 | − 7.71E−06 | − 5.86 | 4.10E−06 | 15 | 88,856,288 | 0.048 |  | No |
45 | cg22581270 | − 7.20E−06 | − 7.01 | 2.39E−07 | 16 | 3,193,156 | 0.007 | CASP16P | Yes |
46 | cg03660158 | 9.88E−06 | 6.19 | 1.77E−06 | 16 | 57,769,342 | 0.027 | KATNB1 | Yes |
 | cg00122310 | 1.30E−05 | 7.79 | 3.84E−08 | 16 | 57,769,432 | 0.002 |  |  |
 | cg00439196 | 1.48E−05 | 8.09 | 1.93E−08 | 16 | 57,769,757 | 0.002 |  |  |
 | cg06830769 | 1.14E−05 | 8.07 | 2.02E−08 | 16 | 57,769,885 | 0.002 |  |  |
47 | cg21854895 | − 1.06E−05 | − 7.92 | 2.81E−08 | 17 | 71,305,638 | 0.002 | CDC42EP4 | Yes |
48 | cg06400109 | 8.45E−06 | 6.18 | 1.83E−06 | 17 | 76,183,118 | 0.027 | AFMID;TK1 | Yes |
 | cg07246050 | 8.44E−06 | 6.86 | 3.44E−07 | 17 | 76,183,123 | 0.009 | AFMID;TK1 |  |
49 | cg21441526 | − 9.09E−06 | − 7.46 | 8.11E−08 | 18 | 21,516,439 | 0.003 | LAMA3 | No |
50 | cg26258423 | − 7.60E−06 | − 6.22 | 1.67E−06 | 18 | 75,380,233 | 0.027 |  | No |
51 | cg27071707 | − 7.31E−06 | − 7.83 | 3.49E−08 | 19 | 1,614,334 | 0.002 | TCF3 | Yes |
52 | cg18788725 | − 7.34E−06 | − 6.07 | 2.40E−06 | 19 | 45,512,122 | 0.033 | RELB | No |
53 | cg04700648 | − 1.03E−05 | − 6.14 | 2.01E−06 | 19 | 52,888,958 | 0.029 | ZNF880 | No |
54 | cg05325193 | 8.85E−06 | 6.86 | 3.47E−07 | 20 | 22,558,233 | 0.009 | C20orf56 | No |
55 | cg25580335 | − 9.10E−06 | − 7.1 | 1.93E−07 | 22 | 24,738,240 | 0.006 | SPECC1L | No |