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Table 1 Main characteristics of the study subjects

From: Novel DNA methylation biomarkers in stool and blood for early detection of colorectal cancer and precancerous lesions

Group

Characteristics

CRC

AA

NED

Tissue

Number

76

  
 

Age (year), n (%)

   
 

 < 40

0 (0%)

  
 

 40–59

24 (31.6%)

  
 

 60–79

42 (55.3%)

  
 

 ≥ 80

10 (13.2%)

  
 

Mean ± SD

64.8 ± 10.8

  
 

Gender, n (%)

   
 

 Male

44 (57.9%)

  
 

 Female

32 (42.1%)

  

Stool

Number

162

46

120

 

Age (year), n (%)

   
 

 < 40

1 (0.6%)

0 (0%)

14 (11.7%)

 

 40–59

48 (29.6%)

19 (41.3%)

77 (64.2%)

 

 60–79

99 (61.1%)

26 (56.5%)

28 (23.3%)

 

 ≥ 80

14 (8.6%)

1 (2.2%)

1 (0.8%)

 

Mean ± SD

64.8 ± 10.7

62.8 ± 7.9

51.6 ± 10.3

 

Gender, n (%)

   
 

 Male

92 (56.8%)

26 (56.5%)

66 (55%)

 

 Female

70 (43.2%)

20 (43.5%)

54 (45%)

Blood

Number

64

17

47

 

Age (year), n (%)

   
 

 < 40

1 (1.6%)

0 (0%)

4 (8.5%)

 

 40–59

21 (32.8%)

7 (41.2%)

16 (34%)

 

 60–79

33 (51.6%)

10 (58.8%)

25 (53.2%)

 

 ≥ 80

9 (14.1%)

0 (0%)

2 (4.3%)

 

Mean ± SD

64.0 ± 12.9

63.5 ± 6.5

61.2 ± 12.7

 

Gender, n (%)

   
 

 Male

40 (62.5%)

9 (52.9%)

35 (74.5%)

 

 Female

24 (37.5%)

8 (47.1%)

12 (25.5%)