Investigating the effects of maltreatment and acute stress on the concordance of blood and DNA methylation methods of estimating immune cell proportions

Table 4 Study 2 multilevel modeling results

Fixed effects: monocytes (lymphocytes)
	Estimate	SE
Intercept	1.156 (− 1.156)	0.78
Sex	0.351 (− 0.351)	1.14
Age	− *1.113 (1.113)*	0.46
BMI	0.313 (− 0.313)	0.19
Ethnicity	*2.474 (− 2.474)*	1.14
Early life adversity	2.519 (− 2.519)	1.40
Time 2	− 0.474 (0.474)	0.94
Time 3	− 0.381 (0.381)	0.96
Time 4	0.936 (− 0.936)	0.97

Random effects
Residual variance	11.52
Individual-level variance	2.63

Immune cell difference scores for monocytes and lymphocytes were modeled as a function of acute stress time-point with sex, age, BMI, ethnicity, and early life adversity status as covariates. Monocyte estimates were reported normally and lymphocyte estimates are reported in parentheses. Random effects for individuals were included for the intercept only
Bold entries indicate a significance level of p < 0.05
* p < 0.05

ISSN: 1868-7083