Fig. 1

Efficacy of chidamide in 28 relapsed/refractory NKTL patients. A Assessment of responses in 28 relapsed/refractory NKTL patients treated with chidamide. CR (5), complete response, 5 patients; PR (6), partial response, 6 patients; SD (2), stable disease, 2 patients; PD (15), progressive disease, 15 patients. Patients with CR or PR were classified as having objective responses, while those with SD or PD were classified as not having objective responses. B Kaplan–Meier curve for PFS of all patients treated with chidamide. C Kaplan–Meier curve for OS of all patients treated with chidamide. D Kaplan–Meier curve comparing the PFS of patients who responded to chidamide (n = 11) with the PFS of those who did not respond (n = 17); p value, log-rank test. E Kaplan–Meier curve comparing the OS of patients who responded to chidamide (n = 11) with the OS of those who did not respond (n = 17); p value, log-rank test. F Swimmer plot showing duration since treatment initiation and clinical outcomes for patients. G Representative images showing tumor lesions (red arrow) before and after chidamide treatment in two relapsed/refractory NKTL patients who achieved CR. Upper images, positron emission tomography-computed tomography (PET-CT) imaging of patient No. 28, throat; lower images, photographs of patient No. 24, left arm