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Fig. 4 | Clinical Epigenetics

Fig. 4

From: E2F1 combined with LINC01004 super-enhancer to promote hepatocellular carcinoma cell proliferation and metastasis

Fig. 4

E2F1 combined with LINC01004 SE to promote its expression. A The IGV results of H3K27ac ChIP-seq, E2F1 ChIP-seq, and ATAC-seq. B E2F1 ChIP-qPCR results of HepG2 cells. IgG antibody was used as negative control. C Correlation analysis of E2F1 and LINC01004 in tumor tissues of TCGA HCC patients. D qRT-PCR results of E2F1 and LINC01004 in HepG2 cells. E Western blot results of E2F1. F Schematic diagram of pGL3-enhancer vectors. G Dual-luciferase reporter system assay of pGL3-enhancer vector. pGL3-basic vector was used as negative control

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