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Table 2 Univariate Cox proportional hazard models for overall survival of gastric cancer patients (n = 97)

From: Inactivation of ZSCAN18 by promoter hypermethylation drives the proliferation via attenuating TP53INP2-mediated autophagy in gastric cancer cells

Predictor

Univariate analysis

HR (95% CI)

p

Gender

Female versus Male

0.916 (0.599–1.401)

0.685

Age (year)

≥ 60 versus < 60

0.986 (0.653–1.487)

0.946

Tumor size (cm)

> 4 versus ≤ 4

1.402 (0.834–2.357)

0.203

Lauren type

Diffuse versus Intestinal

1.079 (0.677–1.721)

0.749

Mix versus Intestinal

1.231 (0.498–3.044)

0.653

Tumor location

Middle 1/3 versus Up 1/3

0.942 (0.531–1.673)

0.839

Low 1/3 versus Up 1/3

0.704 (0.406–1.221)

0.211

 > 2/3 stomach versus Up 1/3

0.880 (0.413–1.873)

0.740

Tumor invasion

pT3-4 versus pT1-2

2.388 (1.293–4.410)

0.005**

Lymph node metastasis

Positive versus Negative

4.758 (2.603–8.698)

< 0.001***

Methylation (high versus low)

CpG11

1.134 (0.722–1.783)

0.585

CpG23

0.852 (0.425–1.708)

0.652

CpG26.27

1.221 (0.532–2.803)

0.637

CpG45.46

2.060 (1.301–3.261)

0.002**

  1. **p < 0.01; ***p < 0.001