Table 1 Demographic and clinical characteristics of subjects
Characteristics | Group | Case–control study | Prospective nested case–control study | ||||||
|---|---|---|---|---|---|---|---|---|---|
Controls | Stroke cases | t/χ2 | P value | Controls | Stroke cases | t/χ2 | P value | ||
(n = 190) | (n = 190) | (n = 144) | (n = 139) | ||||||
Age (mean ± SD, years) | 65.89 ± 10.12 | 64.99 ± 9.85 | 0.884 | 0.377 | 67.77 ± 9.11 | 67.64 ± 9.51 | 0.117 | 0.907 | |
Sex | Male | 83 (43.7%) | 79 (41.6%) | 0.172 | 0.678 | 83 (57.6%) | 81 (58.3%) | 0.012 | 0.914 |
Female | 107 (56.3%) | 111 (58.4%) | 61 (42.4%) | 58 (41.7%) | |||||
SBP (mean ± SD, mmHg) | 148.65 ± 19.76 | 152.44 ± 22.27 | 1.748 | 0.081 | 147.74 ± 20.19 | 147.73 ± 22.28 | 0.005 | 0.996 | |
DBP (mean ± SD, mmHg) | 80.46 ± 11.75 | 85.62 ± 14.42 | 3.814 | 1.60E−04 | 81.50 ± 9.75 | 81.16 ± 11.86 | 0.262 | 0.794 | |
Smoking (n, %) | Yes | 53 (28.0%) | 47 (24.7%) | 0.533 | 0.465 | 36 (25.0%) | 35 (25.2%) | 0.001 | 0.972 |
No | 136 (72.0%) | 143 (75.3%) | 108 (75.0%) | 104 (74.8%) | |||||
Drinking (n, %) | Yes | 69 (36.5%) | 30 (15.8%) | 21.075 | 4.00E−06 | 47 (32.6%) | 47 (33.8%) | 0.044 | 0.834 |
No | 120 (63.5%) | 160 (84.2%) | 97 (67.4%) | 92 (66.2%) | |||||
History of hypertension (n, %) | Yes | 155 (82.0%) | 125 (65.8%) | 12.919 | 0.003 | 87 (60.4%) | 96 (69.1%) | 2.315 | 0.128 |
No | 34 (18.0%) | 65 (34.2%) | 57 (39.6%) | 43 (30.9%) | |||||
History of diabetes (n, %) | Yes | 71 (37.6%) | 51 (26.8%) | 4.992 | 0.025 | 34 (23.6%) | 42 (30.2%) | 1.571 | 0.210 |
No | 118 (62.4%) | 139 (73.2%) | 110 (76.4%) | 97 (69.8%) | |||||
TC (mean ± SD, mmol/L) | 4.84 ± 0.82 | 4.97 ± 4.42 | 0.392 | 0.695 | 5.11 ± 0.91 | 5.20 ± 0.93 | 0.869 | 0.386 | |
TG (mean ± SD, mmol/L) | 1.64 ± 1.29 | 1.80 ± 1.45 | 1.113 | 0.267 | 1.56 ± 1.00 | 1.56 ± 0.88 | 0.014 | 0.989 | |
HDL-C (mean ± SD, mmol/L) | 1.49 ± 0.39 | 1.27 ± 0.38 | 5.453 | 9.13E−08 | 1.54 ± 0.46 | 1.55 ± 0.42 | 0.179 | 0.858 | |
LDL-C (mean ± SD, mmol/L) | 2.65 ± 0.69 | 2.76 ± 2.00 | 0.744 | 0.457 | 2.88 ± 0.80 | 2.96 ± 0.75 | 0.848 | 0.397 | |
Fasting glucose (mean ± SD, mmol/L) | 6.77 ± 2.01 | 6.62 ± 7.26 | 0.254 | 0.800 | 6.61 ± 2.26 | 6.64 ± 2.24 | 0.126 | 0.900 | |