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Fig. 8 | Clinical Epigenetics

Fig. 8

From: Sperm DNA methylome abnormalities occur both pre- and post-treatment in men with Hodgkin disease and testicular cancer

Fig. 8

Sperm DNA methylation of samples post-chemotherapy treatment can still distinguish subjects from each other. Hierarchical clustering of cancer patients post-chemotherapy and baseline CC using the previously discovered A 11,525 significant ANOVA probes and B the top 500 most significant probes. The averaged beta-values of the probes found to differentiate cancer cohorts were used to examine the regions of C SPON2/LOC100130872, D BASP1P1 and E) GDF2 in CC, HD and TC at baseline (solid bars) and post-chemotherapy treatments (hatched bars). Mean ± SEM; t test *p < 0.05, **p < 0.01

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