Fig. 3From: BDNF exon IV promoter methylation and antidepressant action: a complex interplayEffect of single CpG methylation on BDNF exon IV promoter activity. Methylation at CpG position -35, -87 and -39 does not show any significant change in promoter activity in control condition. In the cells treated with ADs, CpG-39 methylation significantly increases the promoter activity (P < 0.0001). Methylation at CpG-35 and -87 had no significant effectBack to article page