Fig. 3From: Longitudinal profiling in patients undergoing cardiac surgery reveals postoperative changes in DNA methylationSignificant DNA methylation changes after cardiac surgery are not a measure of the extent of Inflammation. Of the 96 patients in our study, 20 had preoperative and postoperative IL-6 levels available. Panel (A) shows that IL-6 levels increase significantly from preoperative to postoperative sampling, demonstrating increased inflammation after cardiac surgery. Panels (B) through (F) plot change in DNA methylation at 24Â h by change in IL-6 level at 24Â h for each CpG that has a statistically significant change in DNA methylation after cardiac surgery. Each point on these scatter plots represents one patient sample. A regression line and its accompanying R demonstrate a lack of linear relationship between change in DNA methylation after cardiac surgery and IL-6 levelsBack to article page