Fig. 8From: Epigenetic dysregulation-mediated COL12A1 upregulation predicts worse outcome in intrahepatic cholangiocarcinoma patientsAdministration of miR-424-5p agonist inhibited xenograft tumor growth. A Tumor weight and volume were decreased in AgomiR (MiR-424-5p agonist) group compared with the controls (PBS). B Representative image of H&E and COL12A1 staining in subcutaneous xenograft tumor from AgomiR or control groups. Boxplot showing COL12A1 expression levels in the two groups. ***p < 0.001, using two-tailed Student’s t test.Back to article page