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Fig. 6 | Clinical Epigenetics

Fig. 6

From: Maintenance of methylation profile in imprinting control regions in human induced pluripotent stem cells

Fig. 6

Methylation levels of six PBMC-derived iPSC clones (Three clones of iPSCs from one control individual and from one patient with SRS) cultured with the epiPS™ medium and under hypoxia at 11p15 H19/IGF2:IG-DMR (ICR1) (a), 14q32 DLK1/MEG3:IG-DMR (b), 6q24 PLAGL1:alt-TSS-DMR (c), 7q12 GRB10:DMR (d), 7q32 MEST promoter DMR (e), 11p15 KCNQ1OT1:TSS-DMR (f) and 15q11 PWS/AS:DMR. The hatched part represents the average normal MI area for each locus. MI methylation index, p passage

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Clinical Epigenetics

ISSN: 1868-7083

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