Fig. 6
From: Vitamin C boosts DNA demethylation in TET2 germline mutation carriers
Dynamics of DNA methylation over time with vitamin C supplementation. A Schematic of the methylation/demethylation cycle underlying the reaction rate model. B Two-dimensional arrow plot of the change of rates for the reaction rate model on PBMC enhancer regions. Each arrow stands for an individual, colored by mutation status. The head of the arrow is at percent change of τ (first oxidation step rate) and ρ (further oxidation and repair rate) from 0- to 12-month time point