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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Methylation in MAD1L1 is associated with the severity of suicide attempt and phenotypes of depression

Fig. 4

CpG–phenotype associations. A. Methylation at cg02825527 (β value) in relation to the severity of the suicide attempt in the SKI cohort. Methylation analysis is obtained from the blood sample. p value was derived from a binary logistic regression analysis, where methylation (M value) was used as a predictor and calculated using Wald statistics (implemented natively in R). B. Methylation at cg19624444 (β value) in relation to the severity of the suicide attempt in the SKI cohort. Methylation analysis is obtained from the blood sample. p value was derived from a binary logistic regression analysis, where methylation (M value) was used as a predictor and calculated using the Wald statistics (implemented natively in R). C. Methylation at cg02825527 (β value) in glial cells in relation to the diagnosis in the validation cohort E-GEOD-41826. p value was derived from a binary logistic regression analysis, where methylation (M value) was used as a predictor and calculated using Wald statistics (implemented natively in R)

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