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Table 6 Diagnostic value of CpG1-7 in distinguishing LC from NC or BPN

From: Novel blood-based FUT7 DNA methylation is associated with lung cancer: especially for lung squamous cell carcinoma

 

Specificity (%)

Sensitivity (%)

Positive-LR

Negative-LR

PPV (%)

NPV (%)

LC versus NC

86.19

44.16

3.20

0.65

61.36

75.66

LUAD versus NC

80.97

42.12

2.21

0.71

42.86

80.51

LUSC versus NC

82.48

68.29

3.90

0.38

96.47

27.05

LC versus BPN

56.65

71.43

1.65

0.50

75.12

51.97

LUAD versus BPN

62.23

68.73

1.82

0.50

69.44

61.44

LUSC versus BPN

60.09

75.31

1.89

0.41

87.50

39.61

  1. LC lung cancer, BPN benign pulmonary nodule, NC normal control, LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma, Positive-LR positive likelihood ratio, Negative-LR negative likelihood ratio, PPV positive predictive value, NPV negative predictive value
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Clinical Epigenetics

ISSN: 1868-7083

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