Table 1 Study Characteristics of analytical sample, stratified by cohort
From: Blood DNA methylation signatures of lifestyle exposures: tobacco and alcohol consumption
LBC1921 (N = 550) | LBC1936 (N = 1091) | SKIPOGH (N = 689) | |
|---|---|---|---|
Age (years) | |||
Mean (SD) | 79.3 (0.6) | 69.73 (0.8) | 52.5 (15.5) |
Q1, Q3 | 78.9, 79.7 | 69.1, 70.4 | 41.2, 65.3 |
Missing | 0 | 0 | 0 |
Sex | |||
Male | 238 (41.8%) | 548 (50.2%) | 330 (48.1%) |
Female | 331 (58.2%) | 543 (49.8%) | 356 (51.9%) |
Body mass index (kg/m^2) | |||
Mean (SD) | 26.2 (4.2) | 27. 8 (4.4) | 25.64 (4.7) |
Q1, Q3 | 23.4, 28.5 | 24.9, 30.3 | 22.3, 28.2 |
Missing | 6 | 2 | 1 |
Alcohol unit(s) consumed per week | |||
Mean (SD) | 8.7 (10.1) | 10.5 (14.2) | 6.4 (9.0) |
Q1, Q3 | 2.0, 13.0 | 0.5, 15.0 | 0.0, 9.1 |
Missing | 0 | 0 | 0 |
Alcohol status | |||
Non-drinker | 137 (24.9%) | 211 (19.3%) | 204 (29.9%) |
Moderate drinker | 333 (60.5%) | 686 (62.9%) | 413 (60.6%) |
Heavy drinker | 80 (14.5%) | 194 (17.8%) | 65 (9.5%) |
Smoking status | |||
Non-smoker | 238 (43.4%) | 501 (45.9%) | 288 (42.0%) |
Past smoker | 271 (49.4%) | 465 (42.6%) | 224 (32.7%) |
Current Smoker | 40 (7.3%) | 125 (11.5%) | 174 (25.4%) |
ES: tobacco | |||
Mean (SD) | − 0.1 (2.3) | 0.8 (2.8) | − 1.5 (2.6) |
Q1, Q3 | − 1.4, 1.1 | − 1.0, 2.0 | − 3.0, − 0.6 |
Missing | 115 | 196 | 0 |
ES: alcohol | |||
Mean (SD) | 7.2 (6.6) | 7.6 (7.4) | 8.0 (4.8) |
Q1, Q3 | 3.4, 9.7 | 2.8, 10.8 | 5.1, 9.4 |
Missing | 115 | 196 | 0 |
History of CVD | |||
No CVD | 382 (81.3%) | 823 (75.4%) | 560 (79.3%) |
CVD history | 88 (18.7%) | 268 (24.6%) | 146 (20.7%) |