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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Dynamic patterns of blood lipids and DNA methylation in response to statin therapy

Fig. 4

Longitudinal trajectory of DNA methylation levels in response to statin treatment in Swedish male twins. This figure shows the longitudinal trajectory of DNA methylation levels in response to statin therapy either in raw data (left part) or in predicted data estimated from piecewise latent growth curve model (middle part) in Swedish male twins. Yellow and purple lines shown in the left part of figure represent the longitudinal trend of raw DNA methylation levels for non-statin users and statin users, respectively. Similarly, pink and blue lines in the middle part represent the longitudinal trend of predicted DNA methylation levels derived from piecewise latent growth curve model for non-statin users and statin users. Tables on the right show estimates and P values of the intercepts and slopes of the predicted trajectories in statin users and non-users

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