Fig. 7
From: SLC22A3 methylation-mediated gene silencing predicts adverse prognosis in acute myeloid leukemia
Molecular signatures associated with SLC22A3 in AML. A Heatmap of differentially expressed genes between patients with low- and high-expressed SLC22A3 among Beat AML datasets (FDR < 0.05, P < 0.05, and |log2 FC|> 1.5). B Volcano plot of up- and downregulated genes in lower expressed SLC22A3 group among Beat AML datasets (FDR < 0.05, P < 0.05, and |log2 FC|> 1.5). C Heatmap of differentially expressed genes between AML patients with low- and high-expressed SLC22A3 among TCGA datasets (FDR < 0.05, P < 0.05, and |log2 FC|> 1.5). D Volcano plot of up- and downregulated genes in lower expressed SLC22A3 group among TCGA datasets (FDR < 0.05, P < 0.05, and |log2 FC|> 1.5). E, F Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis of differentially expressed genes among Beat AML datasets by using online website of STRING (http://string-db.org). G, H GO and KEGG analysis of differentially expressed genes among TCGA datasets by using online website of STRING. I Heatmap of differentially expressed microRNAs between AML patients with low- and high-expressed SLC22A3 among TCGA datasets (FDR < 0.05, P < 0.05, and |log2 FC|> 1.5)