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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Epigenome-wide analysis of T-cell large granular lymphocytic leukemia identifies BCL11B as a potential biomarker

Fig. 1

Genome-wide methylation signature of T-LGLL compared to normal T-cell subsets. Unsupervised Principal Component Analysis (PCA) of T-LGLL samples (LGL = purple) and benign T-cell subsets (CD4+ central memory = yellow; CD4+ effector memory = rose; CD4+ naïve = red; CD8+ central memory = green; CD8+ effector memory = blue; CD8+ naïve = gray) of the top two components. Beta-values of 39,930 CpG loci with the highest variation (sd/sdmax> = 0.4) are visualized

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