From: Marijuana use and DNA methylation-based biological age in young adults
 | Year 15 | Year 20 | ||||
---|---|---|---|---|---|---|
0 MJ Years | < 1 MJ Years | ≥ 1 MJ Years | 0 MJ Years | < 1 MJ Years | ≥ 1 MJ Years | |
N | 269 | 539 | 215 | 246 | 441 | 196 |
Female, n (%) | 150 (55.8) | 301 (55.8) | 70 (32.6) | 138 (56.1) | 254 (57.6) | 61 (31.1) |
Race, n (%) | ||||||
 Black | 136 (50.6) | 188 (34.9) | 90 (41.9) | 124 (50.4) | 156 (35.4) | 86 (43.9) |
 White | 133 (49.4) | 351 (65.1) | 125 (58.1) | 122 (49.6) | 285 (64.6) | 110 (56.1) |
Age, mean (SD), years | 39.8 (3.7) | 40.5 (3.4) | 40.9 (3.4) | 44.9 (3.7) | 45.5 (6.3) | 45.7 (3.5) |
IEAA, mean (SD), years | 0.1 (4.4) | 0.0 (4.3) | 0.0 (4.2) | 0.4 (4.1) | − 0.1 (4.5) | − 0.1 (4.4) |
EEAA, mean (SD), years | − 0.4 (5.1) | − 0.1 (5.1) | 0.7 (5.5) | − 0.2 (4.7) | − 0.1 (5.3) | − 0.1 (4.9) |
PAA, mean (SD), years | − 0.3 (5.9) | 0.1 (6.1) | 0.2 (6.1) | 0.0 (6.2) | − 0.2 (6.1) | 0.3 (6.3) |
GAA, mean (SD), years | − 1.3 (3.9) | − 0.3 (4.4) | 2.4 (4.8) | − 1.2 (3.9) | − 0.3 (4.3) | 2.0 (4.8) |
Education, mean (SD), years | 15.3 (2.4) | 15.3 (2.6) | 14.2 (2.4) | 15.3 (2.4) | 15.2 (2.6) | 14.3 (2.4) |
Center, n (%) | ||||||
 Birmingham, AL | 111 (41.3) | 103 (19.1) | 37 (17.2) | 89 (36.1) | 84 (19.0) | 36 (18.4) |
 Chicago, IL | 59 (21.9) | 127 (23.6) | 36 (16.7) | 54 (22.0) | 110 (24.9) | 30 (15.3) |
 Minneapolis, MN | 47 (17.5) | 149 (27.6) | 78 (36.3) | 49 (19.9) | 114 (25.9) | 69 (35.2) |
 Oakland, CA | 52 (19.3) | 160 (29.7) | 64 (29.8) | 54 (22.0) | 133 (30.2) | 61 (31.1) |
Tobacco smoking status, n (%) | ||||||
 Never | 231 (85.9) | 340 (63.1) | 73 (34.0) | 218 (88.6) | 250 (56.7) | 72 (36.7) |
 Former | 17 (6.3) | 106 (19.7) | 51 (23.7) | 12 (4.9) | 107 (24.3) | 52 (26.6) |
 Current | 21 (7.8) | 93 (17.2) | 91 (42.3) | 16 (6.5) | 84 (19.0) | 72 (36.7) |
Lifetime cigarette packs, mean (SD), packs | 499.3 (1886.6) | 1471.6 (2992.5) | 3074.3 (3845.8) | 403.6 (1568.1) | 1843.5 (3285.5) | 3109.4 (4148.0) |
Physical activity, mean (SD), intensity score | 297.1 (259.9) | 351.3 (272.2) | 405.4 (286.3) | 293.8 (253.7) | 349.8 (264.1) | 413.1 (314.6) |
BMI, mean (SD), kg/m2 | 29.4 (7.0) | 28.2 (6.0) | 28.6 (5.7) | 30.3 (7.5) | 29.0 (6.3) | 29.0 (5.4) |
Aspirin use ≥ 3 times per week, n (%) | 12 (4.5) | 35 (6.5) | 13 (6.0) | 30 (12.2) | 54 (12.2) | 25 (12.8) |
Alcohol consumption, mean (SD), mL/day | 4.3 (8.7) | 11.1 (18.2) | 24.2 (36.2) | 4.6 (10.3) | 11.6 (16.7) | 24.4 (49.2) |
Marijuana use in last 30Â days, mean (SD), days | 0 (0) | 0.1 (0.4) | 7.1 (9.6) | 0 (0) | 0.1 (0.5) | 5.8 (9.2) |