Table 1 Characteristics of participants in the EWAS phase

N

1060

948

288

Age, yrs

49.90 ± 12.15

50.56 ± 7.48

49.60 ± 10.05

54.26 ± 10.02

Sex, n (%)

Female

337 (31.8)

416 (43.9)

110 (38.2)

Male

723 (68.2)

532 (56.1)

178 (61.8)

MZ, n (%)

748 (70.6)

–

174 (60.4)

Fasting status, n (%)

≥ 8 h

–

123 (13.0)

–

< 8 h

–

825 (87.0)

–

Smoking status, n (%)

Never

575 (54.2)

514 (54.2)

175 (60.8)

162 (56.3)

Former

136 (12.8)

51 (5.4)

25 (8.7)

45 (15.6)

Current

349 (32.9)

383 (40.4)

88 (30.6)

81 (28.1)

Alcohol consumption, n (%)

Never

539 (50.8)

365 (38.5)

134 (46.5)

125 (43.4)

Former

73 (6.9)

15 (1.6)

9 (3.1)

82 (28.5)

Current

448 (42.3)

568 (59.9)

145 (50.3)

81 (28.1)

BMI, kg/m²

24.83 ± 3.91

23.57 ± 3.49

24.35 ± 3.56

24.46 ± 3.55

TG, mmol/L

1.85 ± 2.00

1.94 ± 1.18

1.86 ± 1.60

1.81 ± 1.34

TC, mmol/L

4.88 ± 1.04

4.58 ± 1.01

4.71 ± 0.98

4.79 ± 0.89

HDL-C, mmol/L

1.36 ± 0.38

1.21 ± 0.30

1.37 ± 0.32

1.29 ± 0.36

LDL-C, mmol/L

2.50 ± 0.77

2.28 ± 0.73

2.13 ± 0.61

2.72 ± 0.81