Fig. 5

Comparison of NDMI 450 and immune profiles in predicting maternal risk factors from cord blood. Three logistic regressions were run on the GEO cord blood datasets, with the independent variable set as the phenotype, and NDMI 450 score (purple), immune cell proportions (green), or NDMI 450 and immune cell proportions (blue) as predictors. Significance is denoted by the shading and shape of the symbol for the model estimate. A GSE152380: 450K, full-term (ref.) versus preterm. NDMI 450 score was significant in the univariate model, and in the model with just cell proportions, NK cell and B cell proportions were significant in distinguishing full-term versus preterm. CD4T cell proportion was a significant predictor in the third model, but NDMI score was not. B GSE104376: 450K, newborns born to low (ref.) versus high anxiety individuals. C GSE153219: 450K, normal for glucose tolerance (ref.) versus gestational diabetes mellitus. In the second model, CD8T cell proportions were a significant predictor. D GSE122288, GSE122086: 850K, normal for glucose tolerance (ref.) versus gestational diabetes mellitus