Fig. 1
From: Whole blood methylome-derived features to discriminate endocrine hypertension
Global structure of blood DNA methylation profile in different hypertension types. a Sample projections based on the first two principle components (PC1, PC2) of unsupervised PCA performed on the whole dataset (n = 731,635 CpG sites, n = 255 samples). The center of each group is indicated by the larger white circles. b Boxplot of the most variable CpG sites (n = 48,452 with M-Value SD > 0.4) in the four hypertension types. #CS, PA and PPGL were aggregated into a single EHT type, with random sampling of 55 samples from each group. *Student’s t-test p value < 0.05