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Fig. 2 | Clinical Epigenetics

Fig. 2

From: 5-Hydroxymethylation alterations in cell-free DNA reflect molecular distinctions of diffuse large B cell lymphoma at different primary sites

Fig. 2

Genome-wide distribution of 5hmC from the plasma cfDNA of individuals in the LN-DLBCL, PT-DLBCL, PCNS-DLBCL, PI-DLBCL, PG-DLBCL and healthy control groups. A Metagene profiles of cell-free 5hmC in the six groups. B The pie chart shows the overall genomic distribution of hMRs in cfDNA. C Normalized enrichment score of hMRs across distinct genomic regions relative to that expected in the 6 groups of samples, with positive values indicating higher than expected enrichment. D Profiles of H3K4me1 and H3K9me3 modifications around distal hMRs in the six groups of samples

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Clinical Epigenetics

ISSN: 1868-7083

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