Table 5 Results from the Cox (proportional hazard) regression models in NICOLA and HRS validation data sets
From: A blood DNA methylation biomarker for predicting short-term risk of cardiovascular events
|  | NICOLA (N = 1728; 83 CVD cases) | HRS (N = 2146; 209 CVD cases) |
|---|---|---|
C-index (95% CI) | C-index (95% CI) | |
DNAmCVDscore | 0.73 (0.68; 0.78) | 0.70 (0.65; 0.73) |
DNAmGrimAge | 0.72 (0.67; 0.77) | 0.70 (0.65; 0.74) |
SCORE2 | 0.72 (0.67; 0.77) | 0.69 (0.65; 0.74) |
MRS | 0.69 (0.64; 0.75) | 0.68 (0.63; 0.72) |
DNAmCVDscore + SCORE2 | 0.75 (0.69; 0.80) | 0.71 (0.67; 0.75) |