Skip to main content

Table 5 Pathway enrichment analysis for significant proteins associated with EXOC4 methylation

From: Altered methylation pattern in EXOC4 is associated with stroke outcome: an epigenome-wide association study

Gene Set

Description

Size

Expect

Ratio

P value

GO:0,030,101

NK cell activation

85

0.21814

27.505

7.13 × 10–04

GO:0,042,110

T cell activation

452

11.600

8.6207

1.40 × 10–03

GO:0,050,673

Epithelial cell proliferation

372

0.95468

9.4272

3.10 × 10–03

GO:0,002,521

Leukocyte differentiation

496

12.729

7.8560

3.30 × 10–03

GO:0,070,661

Leukocyte proliferation

281

0.72115

11.093

4.54 × 10–03

GO:0,001,819

Positive regulation of cytokine production

418

10.727

8.3898

8.24 × 10–03

GO:0,002,250

Adaptive immune response

382

0.98035

8.1604

4.53 × 10–06

GO:0,002,285

Lymphocyte activation involved in immune response

172

0.44141

13.593

4.57 × 10–06

GO:0,018,212

Peptidyl-tyrosine modification

389

0.99831

8.0135

5.17 × 10–06

GO:0,002,449

Lymphocyte mediated immunity

238

0.61079

9.8233

2.9 × 10–05

  1. Description of the significant pathways from Gene Ontology enriched among proteins significantly associated with ΔNIHSS methylation
  2. Size: number of genes included in the gene set; expect: ratio of enrichment expected by chance in the gene set; Ratio: observed ratio for each specific gene set and p value: enrichment p value for each gene set