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Table 1 Clinical characteristics of the study groups, namely HAPE-p, HAPE-f and HLs

From: Differential methylation in EGLN1 associates with blood oxygen saturation and plasma protein levels in high-altitude pulmonary edema

Clinical characteristics

HAPE-p (n = 32)

HAPE-f (n = 32)

HLs (n = 32)

P values

HAPE-p versus HAPE-f

HAPE-p versus HLs

HAPE-f versus HLs

Gender

 Male

28

32

28

   

 Female

4

0

4

NA

> 0.05

NA

Age, years

33.6 ± 11.8

24.2 ± 4.3

44.2 ± 8.4

0.008

< 0.001

< 0.0001

BMI, kg/m2

28.2 ± 6.4

19.9 ± 2.5

21.9 ± 2.5

 < 0.0001

< 0.001

< 0.01

SBP, mmHg

131.2 ± 12.2

121.7 ± 9.4

116 ± 8.4

0.008

< 0.0001

0.020

DBP, mmHg

88.1 ± 7.7

81.0 ± 5.6

69.9 ± 4.8

0.002

< 0.0001

< 0.0001

MAP, mmHg

102.5 ± 11.3

94.6 ± 6.0

85.3 ± 5.0

 < 0.001

< 0.0001

< 0.0001

SpO2 levels, %

67.7 ± 9.7

91.8 ± 4.4

92.3 ± 3.5

 < 0.0001

< 0.0001

NS

  1. Data are presented as mean ± SD and are compared by unpaired student’s t test.
  2. DBP Diastolic blood pressure, MAP Mean arterial pressure, n Number of samples, SpO2 Peripheral blood oxygen saturation, SBP Systolic blood pressure, NS Non-significant, NA Not-applicable