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Fig. 1 | Clinical Epigenetics

Fig. 1

From: Differential methylation in EGLN1 associates with blood oxygen saturation and plasma protein levels in high-altitude pulmonary edema

Fig. 1

Gene expression and biochemical levels in the three study groups, HAPE-p, HAPE-f and HLs. a The relative expression as evaluated by real-time PCR, (i) EGLN1 and (ii) HIF1AN. Values are expressed as fold-change in the HAPE-p and HLs with respect to HAPE-f. b Plasma levels, pg/mL, (i) PHD2 and (ii) FIH-1. Error bar represents the standard error of the mean (SEM); the statistical analysis was done using Student’s t test. Significance was maintained at P ≤ 0.05. EGLN1: Egl nine homolog 1; FIH-1: Factor inhibiting HIF-1α; HIF1AN: Hypoxia Inducible Factor 1 Subunit Alpha Inhibitor; PHD2: Prolyl hydroxylase domain protein 2; HAPE-p: HAPE-patients; HAPE-f: HAPE free controls; HLs: healthy highlanders; *P < 0.05; **P < 0.01; ***P < 0.00; ****P < 0.0001; NS Not significant

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Clinical Epigenetics

ISSN: 1868-7083

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