Table 1 Description of total sample of LISA participants included in this study
From: DNA methylation and aeroallergen sensitization: The chicken or the egg?
Time window A (6 and 10 years) | Time window B (10 and 15 years) | |
|---|---|---|
Total sample size—N | 234 | 227 |
Confounder | ||
Male sex—N (%) [Nmiss] | 135 (57.7%) [0] | 131 (57.7%) [0] |
Exact age at baseline—Mean (sd) [Nmiss] | 6.1 (0.2) [0] | 10.2 (0.1) [0] |
Exact age at follow-up—Mean (sd) [Nmiss] | 10.2 (0.1) [0] | 15.2 (0.2) [52] |
Blood taken in allergy season at baseline—N (%) [Nmiss] | 158 (67.5%) [0] | 116 (51.1%) [0] |
Blood taken in allergy season at follow-up—N (%) [Nmiss] | 124 (53%) [0] | 90 (51.4%) [52] |
BMI measured at baseline—Mean (sd) [Nmiss] | 15.3 (1.3) [1] | 17.0 (2.5) [1] |
BMI measured at follow-up—Mean (sd) [Nmiss] | 16.9 (2.5) [1] | 20.3 (2.8) [59] |
High parental education—N (%) [Nmiss] | 186 (80.2%) [2] | 181 (80.4%) [2] |
N02 at birth address—Mean (sd) [Nmiss] | 21.4 (6.1) [1] | 21.2 (5.5) [1] |
Exposures | ||
(i) Maternal smoking during pregnancy—N (%) [Nmiss] | 17 (7.5%) [7] | 16 (7.2%) [6] |
(ii) At least one parent allergic—N (%) [Nmiss] | 151 (64.5%) [0] | 148 (65.2%) [0] |
(iii) PRS—Mean (sd) [Nmiss] | 0.2 (1.0) [12] | 0.2 (0.9) [11] |
Outcome | ||
Sensitized at baseline—N (%) [Nmiss] | 74 (31.6%) [0] | 101 (44.5%) [0] |
Sensitized at follow-up—N (%) [Nmiss] | 105 (44.9%) [0] | 84 (50.3%) [60] |