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Fig. 6 | Clinical Epigenetics

Fig. 6

From: The absence of AhR in CD4+ T cells in patients with acute graft-versus-host disease may be related to insufficient CTCF expression

Fig. 6

DNA hypermethylation and histone H3K9/14 hypoacetylation of the AhR promoter in CD4+ T cells transfected with the CTCF interference or CTCF expression plasmid. A–C DNA methylation (A) and histone H3K9 (B)/H3K14 C acetylation levels in the AhR promoter region in normal CD4+ T cells transfected with pRS or pRS-CTCF. Data represent the means of three independent experiments. D–F DNA methylation (D) and histone H3K9 (E)/H3K14 F acetylation levels in the AhR promoter of aGVHD CD4+ T cells transfected with pCMV6 or pCMV6-CTCF. Data represent the means of three independent experiments (*P < 0.05)

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Clinical Epigenetics

ISSN: 1868-7083

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