Hypermethylation of tumor suppressor lncRNA MEF2C-AS1 frequently happened in patients at all stages of colorectal carcinogenesis

Table 3 Basic characteristics of in-house patients in three independent steps

Characteristic	In-house step 1	In-house step 2	In-house step 3
	In-house step 1	In-house step 2	Methylation analysis			Expression analysis
	CRC	CRC	NAA	AA	CRC	NAA	AA	CRC
Total	12	48	81	81	286	34	45	75
Age, mean ± SD	63.5 ± 4.2	62.8 ± 9.3	63.5 ± 6.7	62.8 ± 6.6	64.9 ± 11.8	56.9 ± 9.4	61.0 ± 7.0	64.9 ± 12.1
Gender
Male	7	24	40	41	171	20	30	40
Female	5	24	41	40	115	14	15	35
Location
Colon	6	22	60	59	133	33	45	28
Rectum	6	26	21	22	153	1	0	47
TNM stage
I-II	6	24			143			41
III-IV	6	24			143			34
Differentiation
High	7	24			83			32
Middle	4	23			185			41
Low	0	1			6			0
Missing	1	0			12			2

AA, advanced adenoma; CRC, colorectal cancer; NAA, non-advanced adenoma; SD, standard deviation

ISSN: 1868-7083