CpG site | NAA | AA | CRC | p valuea | AA vs. NAA | CRC vs. NAA | CRC vs. AA | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N | β | N | β | N | β |  | Δβ | p valueb | Δβ | p valueb | Δβ | p valueb | |
CpG_1 | 80 | 0.16 | 79 | 0.24 | 283 | 0.23 | 0.009 | 0.08 | 0.049 | 0.07 | 0.008 | − 0.02 | 1.000 |
CpG_3 | 80 | 0.19 | 79 | 0.29 | 283 | 0.27 | 0.001 | 0.10 | 0.008 | 0.08 | 0.001 | − 0.02 | 1.000 |
CpG_4.5.6 | 73 | 0.16 | 75 | 0.23 | 277 | 0.23 | 0.014 | 0.07 | 0.137 | 0.07 | 0.011 | 0.01 | 1.000 |
CpG_7 | 80 | 0.18 | 79 | 0.25 | 282 | 0.24 | 0.087 | 0.07 | – | 0.06 | – | − 0.01 | – |
CpG_8 | 80 | 0.11 | 79 | 0.21 | 283 | 0.18 |  < 0.001 | 0.10 | 0.002 | 0.07 |  < 0.001 | − 0.03 | 1.000 |
CpG_9.10 | 74 | 0.25 | 76 | 0.33 | 276 | 0.33 | 0.012 | 0.08 | 0.079 | 0.08 | 0.010 | 0.00 | 1.000 |
CpG_11 | 80 | 0.15 | 79 | 0.25 | 283 | 0.23 | 0.003 | 0.10 | 0.016 | 0.08 | 0.004 | − 0.02 | 1.000 |
CpG_12 | 80 | 0.20 | 79 | 0.29 | 283 | 0.24 | 0.021 | 0.09 | 0.021 | 0.04 | 0.084 | − 0.04 | 0.714 |
CpG_13 | 80 | 0.16 | 79 | 0.27 | 283 | 0.22 | 0.012 | 0.10 | 0.011 | 0.05 | 0.069 | − 0.05 | 0.515 |
CpG_14.15 | 80 | 0.17 | 79 | 0.27 | 283 | 0.24 | 0.011 | 0.10 | 0.022 | 0.07 | 0.021 | − 0.03 | 1.000 |
CpG_16 | 80 | 0.19 | 79 | 0.29 | 283 | 0.27 | 0.001 | 0.10 | 0.008 | 0.08 | 0.001 | − 0.02 | 1.000 |
CpG_17 | 70 | 0.14 | 73 | 0.19 | 263 | 0.17 | 0.135 | 0.05 | - | 0.03 | - | − 0.02 | - |
CpG_18 | 80 | 0.13 | 79 | 0.21 | 283 | 0.20 | 0.005 | 0.08 | 0.021 | 0.07 | 0.006 | − 0.01 | 1.000 |
CpG_21 | 80 | 0.24 | 79 | 0.29 | 283 | 0.28 | 0.429 | 0.05 | – | 0.03 | – | − 0.02 | – |
CpG_22 | 79 | 0.26 | 79 | 0.32 | 283 | 0.27 | 0.075 | 0.06 | – | 0.01 | – | − 0.05 | – |
CpG_23 | 80 | 0.22 | 79 | 0.33 | 283 | 0.28 | 0.003 | 0.11 | 0.003 | 0.06 | 0.025 | − 0.05 | 0.400 |
CpG_25 | 80 | 0.22 | 79 | 0.33 | 283 | 0.28 | 0.003 | 0.11 | 0.003 | 0.06 | 0.025 | − 0.05 | 0.400 |
CpG_26 | 80 | 0.21 | 78 | 0.34 | 283 | 0.30 | 0.001 | 0.12 | 0.002 | 0.09 | 0.003 | − 0.04 | 1.000 |
Mean | 80 | 0.19 | 79 | 0.28 | 283 | 0.25 | 0.012 | 0.09 | 0.020 | 0.06 | 0.025 | − 0.03 | 1.000 |