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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Genomic targets and selective inhibition of DNA methyltransferase isoforms

Fig. 3

Specificity of hypermethylated loci to DNMT subfamilies and isoforms. A Venn diagram illustrating CpG sites showing gains of methylation of Δβ > 0.2 by DNMT subfamily (blue) and by isoform within the DNMT3A (red), DNMT3B catalytically active (green), DNMT3B catalytically inactive (grey) and DNMTΔ3B (purple) subfamilies. B GO pathway analysis for CpG sites displaying gains of Δβ > 0.2 uniquely in response to overexpression of DNMT3L, DNMT3A1, DNMTΔ3B3 and DNMTΔ3B4

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