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Fig. 16 | Clinical Epigenetics

Fig. 16

From: Epigenetic tumor heterogeneity in the era of single-cell profiling with nanopore sequencing

Fig. 16

The landscape of epigenetic mechanisms. A Cytosine and adenine modification, cytosine by methylation, hydroxymethylation (hmC), formylation (fC), and carboxylation (caC) while adenines by methylation. B Histone modification and nucleosomes having different histone variants change position. C Non-coding RNAs play an important role in transcription regulation and are sometimes considered epigenetic mechanisms. D All RNA modifications can also be considered as a part of epigenetics. Image adapted from [240]

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