Skip to main content
Fig. 5 | Clinical Epigenetics

Fig. 5

From: JIB-04, a histone demethylase Jumonji C domain inhibitor, regulates phenotypic switching of vascular smooth muscle cells

Fig. 5

JIB-04 influenced the mitotic process and induced cell cycle arrest. A. Principal component analysis (PCA) to display the gene expression distribution among the DMSO and JIB-04 groups. B. Differentially expressed genes (DEGs) exhibited by the heatmap were markedly changed after JIB-04 treatment compared to DMSO treatment. C-D. Gene Ontology (GO) enrichment analysis showed that biological processes and cellular components were associated with these DEGs. E. Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment analysis showed different cell cycle-related gene expression patterns in the JIB-04 versus DMSO groups

Back to article page

Clinical Epigenetics

ISSN: 1868-7083

Contact us