Fig. 1From: Integrated multi-omics analyses reveal that BCAM is associated with epigenetic modification and tumor microenvironment subtypes of clear cell renal cell carcinomaBCAM mRNA and protein expression was lower in RCC tissues than in normal kidney tissues. A BCAM mRNA expression in tumor and normal tissues from pan-cancer data of The Cancer Genome Atlas (TCGA). *p < 0.05, **p < 0.01, ***p < 0.001. B BCAM mRNA expression in tumor and normal tissues from ccRCC, pRCC and chRCC obtained from 6 external datasets, including Higgins Renal, Gumz Renal, Beroukhim Renal, Yusenko Renal, Lenburg Renal and Jones Renal. C BCAM mRNA expression in tumor and normal tissues from ccRCC obtained from Gene Expression Omnibus (GEO) database, including GSE53757, GSE40435 and GSE66272. ****p < 0.0001. D Representative microphotographs of BCAM immunohistochemical staining in normal kidney tissue and ccRCC tissue by IHC. E BCAM mRNA expression in the single-cell-type clusters identified in normal kidney tissues. F BCAM protein expression in tumor and adjacent normal tissues from 6 patients in West China Hospital cohort by immunoblotting. The normalized data after quantitative analysis were shown on the right. **p < 0.01. G BCAM protein expression in tumor and normal tissues from ccRCC data of Clinical Proteomic Tumor Analysis Consortium (CPTAC). ***p < 0.001Back to article page