Fig. 4

miR-29c inhibited the proliferation, migration and invasion, colony formation, and growth in 3D Matrigel of breast cancer cells. a Proliferation ofMCF-7 anti-miR-29c is higher than that of MCF-7 Cntl by CCK8 proliferation assay. b Migration and invasion of MCF-7 anti-miR-29cis higher than that ofMCF-7 Cntl. c Proliferation of MDA-MB-231 miR-29c mimic is lower than that MDA-MB-231 Cntl by CCK8 proliferation assay. d Migration and invasion assays of MDA-MB-231 miR-29c mimic are lower than that MDA-MB-231 Cntl. e Colony formations of MCF-7 anti-miR-29c are more than that of MCF-7Cntl in Soft agar assays. f Growth of MCF-7 anti-miR-29c is more than that of MCF-7 Cntl in 3D Matrigel culture. g Colony formations of MDA-MB-231miR-29c mimic are less than that of MDA-MB-231 Cntl in soft agar assays. h Growth of MDA-MB-231 miR-29c mimic is less than that of MDA-MB-231Cntl in 3D Matrigel culture. Data are presented as mean ± SD from three independent experiments, and every experiment was repeated three times, *P < 0.05