Fig. 6

Nomogram model for 1-year and 2-year probability of disease progression. a The scores are 100 for harboring TP53 mutations, 47 for having high mutational load, 73 for harboring ARID family mutations, 17.5 for having EMD, 20 for 1q21 gain and 39.5 for 1q21 amplification. The total points are calculated by summing the scores of each variable and the predicted risk corresponding to the total score is the probability of disease progression. b The ROC plot shows a good performance of this nomogram for 1-year and 2-year PFS. c There is no outlier case detected by Deviance residues test. d Schoenfeld residuals test suggests that the Cox models meet the proportional hazards assumption. e In the validation sets, the AUC and Brier scores of this model are all satisfactory