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Table 1 Confusion matrix of prediction performance of random forest model using 10 CRC-specific methylation CpG sites in distinguishing CRC from normal samples

From: Discovery and validation of tissue-specific DNA methylation as noninvasive diagnostic markers for colorectal cancer

Validation dataset TCGA GSE42752 GSE48684 GSE101764
Accuracy (95% CI) 0.936 (0.909, 0.957) 0.857 (0.746, 0.933) 0.857 (0.775, 0.918) 0.943 (0.907, 0.968)
Balanced accuracy 0.965 0.869 0.839 0.938
Sensitivity 0.929 0.909 0.922 0.902
Specificity 1.000 0.829 0.756 0.973
Kappa 0.728 0.701 0.693 0.882