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Fig. 5 | Clinical Epigenetics

Fig. 5

From: Discovery and validation of tissue-specific DNA methylation as noninvasive diagnostic markers for colorectal cancer

Fig. 5

Validation of specific methylation-based markers in in-house study. A Validation of the methylation markers using target bisulfite sequencing array in validation cohort 3 and cfDNA pilot cohort. Numbers represent average methylation levels of CpG sites in multiple specimens. B and C Validation of the methylation markers using Droplet Digital PCR in cfDNA validation cohort. **P < 0.05. D ROC curves for tissue-specific methylation markers in the cfDNA validation cohort

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