Fig. 3
From: Effect of menopausal hormone therapy on methylation levels in early and late postmenopausal women
Methylation levels at two significantly associated CpG sites as a function of treatment group. Methylation levels (%) for cg19552895 (A) and cg18515510 (B) at baseline and 36 months after treatment are shown in the four treatment groups of women. Significant increases in methylation were observed from baseline (pre) to 36 months after treatment (post) for both CpGs in the late (> 6 years from menopause) HT group but not any of the other three groups. P-values are based on linear regression using M-values for methylation, with adjustment for age, ethnicity, and estimated blood cell fractions