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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Maternal–fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study

Fig. 4

Manhattan plot and Q–Q plot of the association between FSI and salivary DNA methylation. Manhattan plots of salivary DNA methylation associated with FSI (Fetal Stress Index). The x-axis represents the genomic loci of the individual CpGs and the y-axis represents the –log10 (p value). Black line: Bonferroni threshold (p = 6.183879e-08) and the dotted line: Multiple testing correction threshold (FDR < 0.05) has been added to the plot. CpGs that cross the FDR threshold are marked in the Manhattan plot. There are no DMPs that cross the Bonferroni correction threshold. Quantile–quantile (Q–Q) plot shows the expected and the observed quantiles and has a lambda 1.01

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Clinical Epigenetics

ISSN: 1868-7083

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