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Fig. 3 | Clinical Epigenetics

Fig. 3

From: Maternal–fetal stress and DNA methylation signatures in neonatal saliva: an epigenome-wide association study

Fig. 3

Manhattan plot and Q–Q plot of the association between cortisol and salivary DNA methylation. The lambda value for the Q–Q plot is 1.08. Manhattan plots of salivary DNA methylation associated with cortisol. The x-axis represents the genomic loci of the individual CpGs and the y-axis represents the –log10 (p value). Black line: Bonferroni threshold (p = 6.183879e-08) and the dotted line: Multiple testing correction threshold (FDR < 0.05) have been added to the plot. CpGs that cross the FDR threshold are marked in the Manhattan plot. There are four CpGs that cross the FDR multiple correction threshold. Quantile–quantile (QQ) plot shows the expected and the observed quantiles

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Clinical Epigenetics

ISSN: 1868-7083

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