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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Shifts in the immunoepigenomic landscape of monocytes in response to a diabetes-specific social support intervention: a pilot study among Native Hawaiian adults with diabetes

Fig. 4

Association between monocyte immune responses and immune-related gene differential methylation. Plots represent correlation between the delta (Δ) frequency (%) of cytokine-producing monocytes (LPS-stimulated frequency of cytokine-producing monocytes [%] - no stimulation frequency of cytokine-producing monocytes [%]; y-axis) and a–f DNA methylation (β-value; x-axis; left) and g gene expression levels (RPM; x-axis; right) from baseline (orange circle) and post-intervention (green squares) samples for the subset of immune-related DML and DML-enriched DEG, including between a BCL2 & IL-6, b CD6 & IL-6, c DUSP10 & IL-6, d DUSP10 & TNF-α, e FCER2 & IL-β, f FCER2 & IL-6, g FCER2 & IL-1β. Significance taken at P value < 0.05

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Clinical Epigenetics

ISSN: 1868-7083

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