Fig. 6
Chidamide in combination with venetoclax shows synergistical antitumor efficacy in vivo. A Mice were killed, and their tumor masses were fetched and captured by camera. B Tumor weight was measured after detachment. C Tumor volumes were measured every three days after tumor formation. D Mouse body weight was measured every three days after tumor formation. E Immunohistochemistry was performed to investigate the expression of cleaved caspase-3, CDK6, γH2A.X, BCL-XL and BIM in tumor masses. The values indicate mean ± SD for 6 mice/each group (ns P > 0.05; *P < 0.05; ***P < 0.001; ****P < 0.0001)