Fig. 2

The exposure–response pattern (blue lines) with 95% confidence intervals (gray shade) for each lifestyle- and health-related exposure) with other exposures fixed at median). The X-axis represents standardized levels (mean = 0, standard deviation [SD] = 1) of six lifestyle- and health-related exposures. The Y-axis represents GrimAA, in years. A GrimAA of zero (dotted red line) indicates an epigenetic age equal to chronological age. GrimAA less than zero (below the dotted red line) indicates younger epigenetic age compared to chronological age