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Fig. 4 | Clinical Epigenetics

Fig. 4

From: Genome-wide promoter methylation profiling in a cellular model of melanoma progression reveals markers of malignancy and metastasis that predict melanoma survival

Fig. 4

DNA methylation signature associated with melanocyte malignant transformation (malignancy signature). Venn diagram of hypomethylated (A) and hypermethylated (B) genes in common between pairwise comparisons of 4C, 4C11− and 4C11 + versus melan-a cell line. Enrichment plots showing the pathways enriched in Gene Ontology: Biological Process for hypomethylated (C) and hypermethylated (D) genes

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