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Fig. 2 | Clinical Epigenetics

Fig. 2

From: DNA methylation and expression profiles of placenta and umbilical cord blood reveal the characteristics of gestational diabetes mellitus patients and offspring

Fig. 2

Methylation contributes to expression change of genes associated with insulin signaling pathway. A Volcano plot of placenta expression profile. B KEGG pathway enrichment analysis of up-regulated genes in placenta. The numbers in the brackets of the ordinate label represent the number of genes involved. C GSEA analysis of Insulin secretion pathway in placenta expression profile. D The Venn Diagram between DMGs and DEGs in placenta, Fisher’s Exact Test. E KEGG pathway enrichment analysis result of shared genes between DMGs and DEGs in placenta, the numbers in the brackets of the ordinate label represent the number of genes involved. F Correlation between gene methylation and gene expression in placenta, title of each panel shows the gene name and genomic location. Significance was tested by Spearman’s rank correlation test

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Clinical Epigenetics

ISSN: 1868-7083

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